This book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in...
It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot ...
This Open Access 7th edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field.
Discussing all types of stem cell and bone ...
This book uses Pierre Bourdieu's field theory as a lens through which to examine military operations. Novel in its approach, this innovative text provides a better, more nuanced understanding of the modern 'battlespace', particularly in instances of prolonged low-intensity conflict. Formed in two parts, this book primarily explores t...
This volume focuses on microscopic plastic debris, also referred to as microplastics, which have been detected in aquatic environments around the globe and have accordingly raised serious concerns. The book explores whether microplastics represent emerging contaminants in freshwater systems, an area that remains underrepresented to date. Given th...
This book provides a set of conceptual, empirical, and comparative chapters that apply a public policy perspective to investigate the political and institutional factors driving the use of evidence to inform health policy in low, middle, and high income settings. The work presents key findings from the Getting Research Into Policy (GRIP-Health) pro...
This book discusses the important issue of the socioeconomic and environmental impacts of agricultural residue burning, common in agricultural practices in many parts of the world. In particular, it focuses on the pollution caused by rice residue burning using primary survey data from Punjab, India. It discusses emerging solutions to agricultural w...
This book offers new insights into the ageing-migration nexus and the nature of home. Documenting the hidden world of France's migrant worker hostels, it explores why older North and West African men continue to live past retirement age in this sub-standard housing. Conventional wisdom holds that at retirement labour migrants ought to instead ...
The Chinese Economic Transformation, the 19th volume in the China Update book series, provides an opportunity for young economists to share their views on various issues relating to the Chinese economic transformation. More than half of the contributors to this book are female scholars. Some of the contributors are rising stars in the studies of th...
This book uses a critical sociological perspective to explore contemporary ways of reformulating the governance of crime through genetics. Through the lens of scientific knowledge and genetic technology, Machado and Granja offer a unique perspective on current trends in crime governance. They explore the place and role of genetics in criminal justi...
This book marks the first historical overview of the autism rights branch of the neurodiversity movement, describing the activities and rationales of key leaders in their own words since it organized into a unique community in 1992. Sandwiched by editorial chapters that include critical analysis, the book contains 19 chapters by 21 authors about th...
This book explores the conscious and unconscious norms, values, and characteristics that drive behaviors within the high-tech capital of the world, Silicon Valley, and the sector it represents. In an era where the reach and influence of a single industry has the potential to define the future of our world, it has become apparent just how little we ...
This book seeks to foster a multidisciplinary understanding of the ties between faith, financial intermediation, and economic progress by drawing on research across economics, finance, history, philosophy, ethics, theology, public policy, law, and other disciplines. Chapters in this edited volume examine themes as consequential as economic opportun...
This open access collection offers a detailed mapping of recent Nordic literature and its different genres (fiction, poetry, and children's literature) through the perspective of spatiality. Concentrating on contemporary Nordic literature, the book presents a distinctive view on the spatial turn and widens the understanding of Nordic literatur...
You hear it a lot: DevOps is not just about tools, but also about changing company culture. But just how does an organization firmly rooted in traditional software development go about making that change? This in-depth report shows how two large organizations, Nordstrom and Texas.gov, moved from long-established software development models to the c...
If you want to learn how to program, working with Python is an excellent way to start. This hands-on guide takes you through the language a step at a time, beginning with basic programming concepts before moving on to functions, recursion, data structures, and object-oriented design. This second edition and its supporting code have been updated for...
Complexity science uses computation to explore the physical and social sciences. In Think Complexity, you'll use graphs, cellular automata, and agent-based models to study topics in physics, biology, and economics.
Whether you're an intermediate-level Python programmer or a student of computational modeling, you'll delve into exam...
Modeling and Simulation in Python is an introduction to physical modeling using a computational approach. It is organized in three parts:
- The first part presents discrete models, including a bikeshare system and world population growth.
- The second part introduces first-order systems, including models of infectious disease, thermal systems, an...
In a world where web services can make real-time data accessible to anyone, how can the government leverage this openness to improve its operations and increase citizen participation and awareness? Through a collection of essays and case studies, leading visionaries and practitioners both inside and outside of government share their ideas on how to...
Recent reductions in public funding for audiovisual products have led to dramatic changes in the industry. The lack of interaction between the industry and capital markets has made sourcing funds for audiovisual products especially difficult.
This book explains why the distance between the audiovisual and financial markets exists, and considers th...
In this volume, international researchers of the field describe and discuss the systematic review method in its application to research in education. Alongside fundamental methodical considerations, reflections and practice examples are included and provide an introduction and overview on systematic reviews in education research.
Reflections on th...
Carried by a long-awaited wind, the chlorine cloud passed within a few minutes through the British and French trenches, leaving behind at least 1,000 dead and 4,000 injured. This chemical attack, which amounted to the first use of a weapon of mass destruction, marks a turning point in world history. The preparation as well as the execution of the g...
This free book offers a novel view on the benefits of a lasting variation between the member states in the EU. In order to bring together thirty very different European states and their citizens, the EU will have to offer more scope for variation. Unlike the existing differentiation by means of opt-outs and deviations, variation is not a concession...
Conviviality has lately become a catchword not only in academia but also among political activists. This open access book discusses conviviality in relation to the adjoining concepts cosmopolitanism and creolisation. The urgency of today's global predicament is not only an argument for the revival of all three concepts, but also a reason to br...
This book offers pioneering insights and practical methods for promoting diversity and inclusion in higher education classrooms and curricula. It highlights the growing importance of international education programs in Asia and the value of understanding student diversity in a changing, evermore interconnected world. The book explores diversity acr...
This free book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a r...
This book provides insight into the implementation of Life Cycle approaches along the entire business value chain, supporting environmental, social and economic sustainability related to the development of industrial technologies, products, services and policies; and the development and management of smart agricultural systems, smart mobility syste...
This book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio.Latinos – the largest, youngest, and fastest-grow...
This book establishes the foundations needed to realize the ultimate goals for artificial intelligence, such as autonomy and trustworthiness. Aimed at scientists, researchers, technologists, practitioners, and students, it brings together contributions offering the basics, the challenges and the state-of-the-art on trusted autonomous systems in a s...
This book offers both conceptual and empirical descriptions of how to "frame" sustainability challenges. It defines "framing" in the context of sustainability science as the process of identifying subjects, setting boundaries, and defining problems. The chapters are grouped into two sections: a conceptual section and a case sect...
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes 'macro-connectome' efforts to comprehensively chart long-distance pathways and functional networks; 'micro-connectome' efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted ...
This book presents a qualitative longitudinal panel-study on child and adolescent socialisation in socially disadvantaged families. The study traces how children and their parents make sense of media within the context of their everyday life over twelve years (from 2005 to 2017) and provides a unique perspective on the role of different socialisati...