This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are i...
This book presents the deterministic view of quantum mechanics developed by Nobel Laureate Gerard 't Hooft.Dissatisfied with the uncomfortable gaps in the way conventional quantum mechanics meshes with the classical world, 't Hooft has revived the old hidden variable ideas, but now in a much more systematic way than usual. In this, quantu...
Complexity science uses computation to explore the physical and social sciences. In Think Complexity, you'll use graphs, cellular automata, and agent-based models to study topics in physics, biology, and economics.
Whether you're an intermediate-level Python programmer or a student of computational modeling, you'll delve into exam...
Introduction to the Modeling and Analysis of Complex Systems introduces students to mathematical/computational modeling and analysis developed in the emerging interdisciplinary field of Complex Systems Science. Complex systems are systems made of a large number of microscopic components interacting with each other in nontrivial ways. Many real-worl...
This open book provides a concise yet comprehensive overview on how to build a quality management program for hematopoietic stem cell transplantation (HSCT) and cellular therapy. The text reviews all the essential steps and elements necessary for establishing a quality management program and achieving accreditation in HSCT and cellular therapy. Spe...
This Open Access 7th edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field.
Discussing all types of stem cell and bone ...
This free book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a r...
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides ...
How can we capture the unpredictable evolutionary and emergent properties of nature in software? How can understanding the mathematical principles behind our physical world help us to create digital worlds? This book focuses on a range of programming strategies and techniques behind computer simulations of natural systems, from elementary concepts ...
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clini...
The first book of its kind, this work discusses the global extent of ranaviruses, principles of ranavirus ecology and evolution. The research included provides guidance on designing ranavirus surveillance studies to determine risk. Ranaviruses are are double-stranded DNA viruses that cause hemorrhagic disease in amphibians, reptiles, and fish. Rana...
This open book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients.
Diagnostic and therapeutic technologies continue ...
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspe...
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyse...
This book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecula...
This book presents theoretical framework and sample applications of variant construction. The first part includes the components variant logic, variant measurements, and variant maps, while the second part covers sample applications such as variation with functions, variant stream ciphers, quantum interference, classical/quantum random sequences, w...
This book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regula...
SAT/SMT solvers can be viewed as solvers of huge systems of equations. The difference is that SMT solvers takes systems in arbitrary format, while SAT solvers are limited to boolean equations in CNF 1 form. A lot of real world problems can be represented as problems of solving system of equations....
This open access State-of-the-Art Survey presents the main recent scientific outcomes in the area of reversible computation, focusing on those that have emerged during COST Action IC1405 "Reversible Computation - Extending Horizons of Computing", a European research network that operated from May 2015 to April 2019.Reversible computation ...
This edited volume explores new engagements with the life sciences in contemporary fiction, poetry, comics and performance. The gathered case studies investigate how recent creative work reframes the human within microscopic or macroscopic scales, from cellular biology to systems ecology, and engages with the ethical, philosophical, and political i...