This book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sectio...
Beginning with an overview of data and concepts developed in the EU-project HABIT-CHANGE, this book addresses the need for sharing knowledge and experience in the field of biodiversity conservation and climate change. There is an urgent need to build capacity in protected areas to monitor, assess, manage and report the effects of climate change and...
Phylogenetic diversity is now a key concept for biodiversity conservation due to its link to option value, evolutionary potential and to the possibility of guiding conservation across scales. Present facilities for obtaining molecular sequences and metagenomes are powering this research field, rendering available detailed information of phylogeneti...
The Tohoku University Graduate School of Dentistry first introduced the concept of "Interface Oral Health Science", designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are: (1) host tissues such as teeth, mucosa, muscle and bone, (2) parasites and microorganis...
This book contains the joint proceedings of the Winter School of Hakodate (WSH) 2011 held in Hakodate, Japan, March 15–16, 2011, and the 6th International Workshop on Natural Computing (6th IWNC) held in Tokyo, Japan, March 28–30, 2012, organized by the Special Interest Group of Natural Computing (SIG-NAC), the Japanese Society for Artificial I...
This book provides methods for the estimation of Biomass Water Equivalent (BEW), an essential step for improving the accuracy of area-wide soil moisture by cosmic-ray neutron sensors (CRNS). Three techniques are explained in detail: (i) traditional in-situ destructive sampling, (ii) satellite based remote sensing of plant surfaces, and (iii) biom...
This book provides a unique overview of the impacts of railways on biodiversity, integrating the existing knowledge on the ecological effects of railways on wildlife, identifying major knowledge gaps and research directions and presenting the emerging field of railway ecology. The book is divided into two major parts: Part one offers a general revi...
To understand how the world's ecosystems are changing we need to understand cities, and to create better cities we need to understand the ecosystems they depend on. The failure of most markets, government policies and even urban studies to take these relations into account has put cities, and increasingly the whole world, in a difficult positi...
This free book provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine....
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications.
The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study ...
This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation. It addresses these aspects through a series of over 400 computer problems, ranging from elementary to research level to enable learning by doing. Students solve the ...
This casebook provides a set of cases that reveal the current complexity of medical decision-making, ethical reasoning, and communication at the end of life for hospitalized patients and those who care for and about them. End-of-life issues are a controversial part of medical practice and of everyday life. Working through these cases illuminates bo...
Additive manufacturing or 3D printing, manufacturing a product layer by layer, offers large design freedom and faster product development cycles, as well as low startup cost of production, on-demand production and local production. In principle, any product could be made by additive manufacturing. Even food and living organic cells can be printed. ...
In Molecular Feminisms, Roy investigates science as feminism at the lab bench, engaging in an interdisciplinary conversation between molecular biology, Deleuzian philosophies, posthumanism, and postcolonial and decolonial studies. She brings insights from feminist theory together with lessons learned from bacteria, subcloning, and synthetic biology...
Everything Flows explores the metaphysical thesis that the living world is not made up of substantial particles or things, as has often been supposed, but is rather constituted by processes. The biological domain is organised as an interdependent hierarchy of processes, which are stabilized and actively maintained at different timescales. Even enti...
This open book explores how biometric data is increasingly flowing across borders in order to limit, control and contain the mobility of selected people, namely criminalized populations. It introduces the concept of bio-bordering, using it to capture reverse patterns of bordering and ordering practices linked to transnational biometric data exchang...
This open book focuses on the discrepancies in biobank research regulations that are among the most significant hurdles to effective research collaboration. The General Data Protection Regulation (GDPR) has established stringent requirements for the processing of health and genetic data, while simultaneously allowing considerable multi-level except...
This open volume aims to methodologically improve our understanding of biodiversity by linking disciplines that incorporate remote sensing, and uniting data and perspectives in the fields of biology, landscape ecology, and geography. The book provides a framework for how biodiversity can be detected and evaluated - focusing particularly on plants -...
Aquatic ecosystems are rich in biodiversity and home to a diverse array of species and habitats, providing a wide variety of benefits to human beings. Many of these valuable ecosystems are at risk of being irreversibly damaged by human activities and pressures, including pollution, contamination, invasive species, overfishing and climate change. Su...
This book analyzes the possibilities for effective global governance of science in Europe, India and China. Authors from the three regions join forces to explore how ethical concerns over new technologies can be incorporated into global science and technology policies. The first chapter introduces the topic, offering a global perspective on embeddi...
This book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and imag...
The oceans and atmosphere interact through various processes, including the transfer of momentum, heat, gases and particles. In this book leading international experts come together to provide a state-of-the-art account of these exchanges and their role in the Earth-system, with particular focus on gases and particles. Chapters in the book cover: ...
We are not free from environmental risks that accompany the development of human societies. Modern economic development has accelerated environmental pollution, caused loss of natural habitats, and modified landscapes. These environmental changes have impacted natural systems: water and heat circulation, nutrient cycling, and biodiversity. These ch...
This book describes in vitro and ex vivo models that can be employed to investigate effects of digested food products on the GIT, or specific components thereof. Many such models exist and include, for example, those used to study digestion and fermentation in the small and large intestine, to investigate absorption (e.g. Ussing chamber, epithelial...
This book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecula...
This open access volume is the first comprehensive assessment of the Hindu Kush Himalaya (HKH) region. It comprises important scientific research on the social, economic, and environmental pillars of sustainable mountain development and will serve as a basis for evidence-based decision-making to safeguard the environment and advance people's w...
This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as th...
This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan p...
This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part I makes key concepts in statistics readily clear. Parts I and II give an overview of the most common tests (t-test, ANOVA, correlations) and work out their statistical principles. Part III pr...
This proceedings is a collection of 46 selected papers that were presented at the 12th International Wheat Genetics Symposium (IWGS). Since the launch of the wheat genome sequencing project in 2005, the arrival of draft genome sequences has marked a new era in wheat genetics and genomics, catalyzing rapid advancement in the field. This book provide...
This book aims to provide case studies and a general view of the main processes involved in the ecosystem shifts occurring in the high mountains, and to analyse the implications for nature conservation. Although case studies from the Pyrenees are preponderant, conclusions are aimed at any mountain range surrounded by highly populated lowland areas....
This book covers the latest in snow sport epidemiology, snow sport injuries and treatment, and biomechanical/mechanical engineering related to snow sports injuries (mechanisms of injury, injury prevention by equipment design, injury prevention by design of resort features, and more). It brings together a collection of papers from the International ...