BIOINFORMATICS

Applied Bioinformatics

by Paul M. Selzer, Richard J. Marhöfer, Oliver Koch

This book introduces readers to the basic principles of bioinformatics and the practical application and utilization of computational tools, without assuming any prior background in programming or informatics. It provides a coherent overview of the complex field and focuses on the implementation of online tools, genome databases and software that c...

Bioinformatics for Evolutionary Biologists

by Bernhard Haubold, Angelika Börsch-Haubold

This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation. It addresses these aspects through a series of over 400 computer problems, ranging from elementary to research level to enable learning by doing. Students solve the ...

The Gene Ontology Handbook

by Christophe Dessimoz, Nives Škunca

This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyse...

Evolutionary Genomics

by Maria Anisimova

This book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sectio...

Data and Text Processing for Health and Life Sciences

by Francisco Couto

This book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and...

High-Performance Modelling and Simulation for Big Data Applications

by Joanna Kołodziej, Horacio González-Vélez

This book is the final compendium of case studies emanated from the 4-year COST Action IC1406 "High-Performance Modelling and Simulation for Big Data Applications" (cHiPSet). Funded by the European Commission from 2015, cHiPSet has created a sustainable reference network linking applied research in High Performance Computing (HPC) and Mod...

Natural Computing and Beyond

by Yasuhiro Suzuki, Toshiyuki Nakagaki

This book contains the joint proceedings of the Winter School of Hakodate (WSH) 2011 held in Hakodate, Japan, March 15–16, 2011, and the 6th International Workshop on Natural Computing (6th IWNC) held in Tokyo, Japan, March 28–30, 2012, organized by the Special Interest Group of Natural Computing (SIG-NAC), the Japanese Society for Artificial I...

Fundamentals of Clinical Data Science

by Pieter Kubben, Michel Dumontier, Andre Dekker

This book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using tec...

Statistical Population Genomics

by Julien Y. Dutheil

This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demog...

Bioimage Data Analysis Workflows

by Kota Miura, Nataša Sladoje

This Open Access textbook provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by step protocols to familiarize readers with the most commonly used image processing and analysis platf...