This open access volume is the first comprehensive assessment of the Hindu Kush Himalaya (HKH) region. It comprises important scientific research on the social, economic, and environmental pillars of sustainable mountain development and will serve as a basis for evidence-based decision-making to safeguard the environment and advance people's w...
This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are i...
This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part I makes key concepts in statistics readily clear. Parts I and II give an overview of the most common tests (t-test, ANOVA, correlations) and work out their statistical principles. Part III pr...
This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular charac...
This edited volume examines the policies and practices of rising powers on peacebuilding. It analyzes how and why their approaches differ from those of traditional donors and multilateral institutions. The policies of the rising powers towards peacebuilding may significantly influence how the UN and others undertake peacebuilding in the future. Thi...
Phylogenetic diversity is now a key concept for biodiversity conservation due to its link to option value, evolutionary potential and to the possibility of guiding conservation across scales. Present facilities for obtaining molecular sequences and metagenomes are powering this research field, rendering available detailed information of phylogeneti...
In this Handbook of Experimental Pharmacology on "High Density Lipoproteins – from biological understanding to clinical exploitation" contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several dise...
This book, published in the Soft and Biological Matter series, presents an introduction to selected research topics in the broad field of flowing matter, including the dynamics of fluids with a complex internal structure -from nematic fluids to soft glasses- as well as active matter and turbulent phenomena.Flowing matter is a subject at the crossro...
Missy Maker is a middle school girl who loves math and fashion. She sees math in everything she does. She tries to hide this from her friends, because she thinks it's too geeky. Missy hears that the school math club needs more members, but she's worried about what her friends will think if she joins, and she's already committed to jo...
This book facilitates an integrative understanding of the development, genetics and evolution of butterfly wing patterns. To develop a deep and realistic understanding of the diversity and evolution of butterfly wing patterns, it is essential and necessary to approach the problem from various kinds of key research fields such as "evo-devo,&quo...
This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews re...
This book is a result of the first ever study of the transformations of the higher education institutional landscape in fifteen former USSR countries after the dissolution of the Soviet Union in 1991. It explores how the single Soviet model that developed across the vast and diverse territory of the Soviet Union over several decades has evolved int...
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médec...
The average person can name more bird species than they think, but do we really know what a bird "species" is? This book takes up several fascinating aspects of bird life to elucidate this basic concept in biology. From genetic and physiological basics to the phenomena of bird song and bird migration, it analyzes various interactions of b...
This open access, interdisciplinary book presents innovative strategies in the use of civil drones in the cultural and creative industry. Specially aimed at small and medium-sized enterprises (SMEs), the book offers valuable insights from the fields of marketing, engineering, arts and management. With contributions from experts representing varied ...
This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for eva...
This book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio.Latinos – the largest, youngest, and fastest-grow...
This free book is the first comprehensive guide to a new soft computing technique which is used in complex forensic cases. The chapters include detailed technical and practical overviews, and discussions about the latest tools, open problems and ethical and legal issues involved. The book will be of interest to researchers and practitioners in fore...
The 1960s was a time of reform and revolution in America, brought on by individuals willing to challenge political, social, and cultural norms. Politics, Power, & Playboy explores the American mindset during this turbulent and transformative time in American history. Each chapter examines instances of Americans confronting power, whether it be ...
This book is about making machine learning models and their decisions interpretable. After exploring the concepts of interpretability, you will learn about simple, interpretable models such as decision trees, decision rules and linear regression. Later chapters focus on general model-agnostic methods for interpreting black box models like feature i...
This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation. It addresses these aspects through a series of over 400 computer problems, ranging from elementary to research level to enable learning by doing. Students solve the ...
This 3rd edition of the highly successful book, acclaimed for its comprehensiveness, accuracy, and excellent illustrations and photographs now comes with updated coverage plus numerous didactical improvements:The number of figures has notably increased, with about one third of them now presented in color. More photographs and schematics make it eas...
This enzymology textbook for graduate and advanced undergraduate students covers the syllabi of most universities where this subject is regularly taught. It focuses on the synchrony between the two broad mechanistic facets of enzymology: the chemical and the kinetic, and also highlights the synergy between enzyme structure and mechanism. Designed f...
This third edition laboratory manual was written to accompany Food Analysis, Fifth Edition, by the same author. New to this third edition of the laboratory manual are four introductory chapters that complement both the textbook chapters and the laboratory exercises. The 24 laboratory exercises in the manual cover 21 of the 35 chapters in the textbo...
This book contains 157 problems in classical electromagnetism, most of them new and original compared to those found in other textbooks. Each problem is presented with a title in order to highlight its inspiration in different areas of physics or technology, so that the book is also a survey of historical discoveries and applications of classical e...
This book introduces readers to the basic principles of bioinformatics and the practical application and utilization of computational tools, without assuming any prior background in programming or informatics. It provides a coherent overview of the complex field and focuses on the implementation of online tools, genome databases and software that c...
Until recently, most grape-based wine was consumed close to where it was produced, and mostly that was in Europe. Despite the huge growth in inter-continental trade, investment and migration during the first globalization wave that came to a halt with World War I, it was not until the 1990s that the export share of global wine production rose above...
This book shows us that the way to master complexity is through insight rather than precision. Precision can overwhelm us with information, whereas insight connects seemingly disparate pieces of information into a simple picture. Unlike computers, humans depend on insight. Based on the author's fifteen years of teaching at MIT, Cambridge Unive...
Physiology - The word physiology is from the Ancient Greek (phusiología) and it is the study of how organisms perform their vital functions. An example is the study of how a muscle contracts or the force contracting muscles exert on the skeleton. It was introduced by French physician Jean Fernery in 1552. Physiology is built upon a tripod of scien...
Everything Flows explores the metaphysical thesis that the living world is not made up of substantial particles or things, as has often been supposed, but is rather constituted by processes. The biological domain is organised as an interdependent hierarchy of processes, which are stabilized and actively maintained at different timescales. Even enti...
Have you ever looked deep into the eyes of an animal and felt entirely known? Often, the connections we share with non-human animals represent our safest and most reliable relationships, offering unique and profound opportunities for healing in periods of hardship. This book focuses on research developments, models, and practical applications of hu...
This open volume provides readers with an open access protocol collection and wide-ranging recommendations for preclinical renal MRI used in translational research. The chapters in this book are interdisciplinary in nature and bridge the gaps between physics, physiology, and medicine. They are designed to enhance training in renal MRI sciences and ...